A team of scientists have attempted to insert an alligator gene into the genomes of catfish for the purpose of reducing disease in farmed fish as about 40% of them die from infections. US fish farms produced 307 million tons of catfish in 2021. Rex Dunham, who works at Auburn University in Alabama, hopes that an alligator gene that codes for a protein called cathelicidin that he says acts an antimicrobial will help animals that have the gene artificially inserted into their genomes to become more resistant to diseases. An experiment showed that the fish, genetically modified using CRISPR technology, had a between two- and five-fold higher when exposed to bacteria.
Genetically modified animals have the potential to wreak havoc in the wild should they escape from farms, outcompeting their wild counterparts for food and habitat.
Millions of fish are farmed in the US every year, but many of them die from infections. In theory, genetically engineering fish with genes that protect them from disease could reduce waste and help limit the environmental impact of fish farming. A team of scientists have attempted to do just that—by inserting an alligator gene into the genomes of catfish.
Americans go through a lot of catfish. In 2021, catfish farms in the US produced 307 million pounds (139 million kilogram) of the fish. “On a per-pound basis, anywhere from 60 to 70% of US aquaculture is … catfish production,” says Rex Dunham, who works on the genetic improvement of catfish at Auburn University in Alabama.
But catfish farming is also a great breeding ground for infections. From the time farmed fish are newly hatched to the time they are harvested, around 40% of the animals worldwide die from various diseases, says Dunham.
Could the new genetic modification help?
The alligator gene, which Dunham’s research turned up as a potential answer, codes for a protein called cathelicidin. The protein is antimicrobial, says Dunham—it’s thought to help protect alligators from developing infections in the wounds they sustain during their aggressive fights with each other. Dunham wondered whether animals that have the gene artificially inserted into their genomes might be more resistant to diseases.
Dunham and his colleagues also wanted to go a step further and ensure that the resulting transgenic fish couldn’t reproduce. That’s because genetically modified animals have the potential to wreak havoc in the wild should they escape from farms, outcompeting their wild counterparts for food and habitat.
Dunham, Baofeng Su (also at Auburn University), and their colleagues used the gene-editing tool CRISPR to insert the alligator gene for cathelicidin into the part of the genome that codes for an important reproductive hormone, “to try to kill two birds with one stone,” says Dunham. Without the hormone, fish are unable to spawn.
The resulting fish do seem to be more resistant to infections. When the researchers put two different types of disease-causing bacteria in water tanks, they found that gene-edited fish were much more likely to survive than their counterparts that had not undergone gene editing. Depending on the infection, “the survival rate of the cathelicidin transgenic fish was between two- and five-fold higher,” says Dunham.
The transgenic fish are also sterile and can’t reproduce unless they are injected with reproductive hormones, say the researchers, who published their findings online at the preprint server bioRxiv. The paper has not yet been peer-reviewed.
“When I first [heard about the study], I thought: what on earth? Who would have thought to do this? And why would they?” says Greg Lutz at Louisiana State University, who has been researching the role of genetics in aquaculture for decades. But Lutz thinks the work has promise—disease resistance can have a big impact on the amount of waste generated by fish farms, and reducing this waste has long been a goal of gene editing in farmed animals, he says.
Farming fish that are resistant to disease will require fewer resources and produce less waste overall, he says. Though Lutz is positive about the research, he isn’t convinced that the CRISPR catfish represent the future of aquaculture. The gene-editing procedure used by the team is fiddly, and it would probably need to be done for each round of fish spawning for the hybrid catfish commonly used in fish farming. “It’s just too difficult to produce enough of these fish to get a viable, genetically healthy line going,” he says.
Dr. Cowan described a ‘playbook’ to convince doctors of a highly lethal ‘syndrome’ that is poorly defined and could mean just about anything. Doctors then convince the public. In the early days, people are often sent to hospitals and given protocols that become the standard of care, but are deadly.
Last week, the Proud Boys’ trial was suspended again after prosecutors revealed that a paid FBI informant cozied up to defendants and their attorneys. At least 10 and up to 15 FBI informants were embedded in the group months before and continuing after the events of January 6.
ChatGPT can now access the internet, run its own code to solve problems, accept and work on uploaded files, and write its own interfaces to third-party apps. There is concern over whether it may escape its boundaries and engage in “power-seeking behavior” it’s already been caught exhibiting.
Audrey Hale, a 28-year old woman who had transitioned into a male, blasted her way into the Covenant Church school hunting for victims and reportedly killed three 9-year old students and three staff members. Hale was also killed.
Dr. Hyman said that for every 10% of calories consumed from ultra-processed food, the risk of death goes up by 14%. The American diet is 60% ultra-processed food, and for children it is 67%. Eleven million die globally from bad food.
Video shows Fauci admitting “I got my second vaccine yesterday, and I feel like sh*t today!” In another segment, a DC resident told Fauci that he didn’t trust the jab or the hurried science that went into creating it. The man continued and said the COVID vaccine campaign was about attacking people using fear.
has used hormones and has received sex-change surgeries, and now shows signs of regret. Instead of receiving treatment for mental health issues, children are being encouraged to change gender by taking hormones and undergoing major surgeries that can alter their bodies irreversibly.
A prior injunction blocked the mandate in January 2022, only a few months after Biden issued the order, but nearly 98% of covered employees had already been vaccinated. Opponents of the policy said it was an encroachment on federal workers’ lives that neither the Constitution nor federal statutes authorize.
Since the CDC started collecting the data autism has skyrocketed from 1 in 150 in 2000, to today’s estimate of 1 in 36 children. The report failed to address the causes of autism, but claimed the rising rate was due to increased testing.
California produces half of America’s agriculture that includes fruits, vegetables and nuts, in addition to dairy products, cattle and rice. Almost half of California’s agricultural products are exported to other countries. We await the impact on food supplies.
DeSouza said that the cabal of money lenders from “banking bloodlines” has dominion over the UAPs and is building a campaign of fear. He said that the next step is for UAPs to start shooting down commercial airliners and military jets. A ‘Fake Alien Invasion’ will be a psy-op. But the destruction will be real.
Biden released a proposed budget for fiscal year 2024 totaling $6.9 trillion that included over $4.7 trillion in new tax increases, including a 20% hike in the capital gains tax rate and a 7.6% increase in the top income tax rate.
The Arizona Supreme Court ruled that Kari Lake will be allowed to expose the Signature Verification security system on mail-in ballots. Lake said that Adrian Fontes, the current AZ Secretary of State, who was the Maricopa County Recorder during the contested 2020 election, is a Mexican drug cartel attorney and a fraud.
Pilot Josh Yoder reported that as many as 80% of pilots have taken COVID jabs, as many airlines mandated it. He said it is no longer safe to fly as there have been many incidents of pilots becoming incapacitated, but there is a massive coverup underway.
Shocking video shows soldiers in Ukraine kidnap and forcibly conscript men in broad daylight to fight in the the losing war against Russia. Over 100,000 Ukrainians are dead, but US warmongers in power push for more war in the proxy battle against Russia.
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Chinese scientists have used gene editing to make the brains of monkeys more human-like by editing the human version of a gene known as ‘MCPH1’ into the macaques. The gene-hacked monkeys showed better reaction times and improved short-term memories.
What about unintended consequences? The CRISPR technique is simple, raising the fear that the technology will be used by ignorant and unethical people. Scientists worry that once a species is modified, it is changed forever.
A new study shows that CRISPR gene editing can cause hundreds of unintended gene mutations. DNA tinkering is part of a long-standing program, originally funded by the Rockefellers, to transform the human race into two distinct species: one to serve and the other to command.
There is a reason the catfish are suffering from diseases. Trying to bypass the actual solution to these diseases (due probably to overcrowding, poor nutrition, polluted water) is likely going to put an unhealthy product on the market, poisoning the consumers.
These scientists continue to vandalize nature with their irresponsible genetic tinkering.
Can you say ..J.U.R.A.S.S.I.C…P.A.R.K. ????
For heavens sake STOP FUNDING THESE FRANKENSTEIN-wannabes..
Always trying to screw with mother nature. None of these scientists have come close to what our creator gave us.